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Y Akao Selected Research

salsoline

5/2002Mitochondria determine the survival and death in apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, and neuroprotection by propargylamines.
1/2000Involvement of endogenous N-methyl(R)salsolinol in Parkinson's disease: induction of apoptosis and protection by (-)deprenyl.
1/2000Neurotoxins induce apoptosis in dopamine neurons: protection by N-propargylamine-1(R)- and (S)-aminoindan, rasagiline and TV1022.

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Y Akao Research Topics

Disease

7Parkinson Disease (Parkinson's Disease)
01/2007 - 01/2000
5Neoplasms (Cancer)
06/2010 - 03/2000
5Neuroblastoma
02/2006 - 01/2000
4Leukemia
11/2006 - 10/2000
3Melanoma (Melanoma, Malignant)
12/2016 - 12/2012
3Adenoma (Adenomas)
06/2010 - 11/2000
3Colorectal Neoplasms (Colorectal Cancer)
06/2010 - 11/2000
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2007 - 01/2006
2Mitochondrial Diseases (Mitochondrial Disease)
05/2006 - 01/2006
2Carcinogenesis
07/2003 - 12/2001
2B-Cell Lymphoma (Lymphoma, B Cell)
07/2003 - 12/2001
1Urinary Bladder Neoplasms (Bladder Cancer)
02/2013
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
11/2006
1Alzheimer Disease (Alzheimer's Disease)
02/2006
1Hepatocellular Carcinoma (Hepatoma)
07/2003
1Chronic Hepatitis (Chronic Active Hepatitis)
07/2003
1Genetic Translocation (Chromosomal Translocation)
12/2001
1Carcinoma (Carcinomatosis)
11/2000
1Kidney Neoplasms (Kidney Cancer)
11/2000
1Acute Promyelocytic Leukemia
10/2000
1Hyperthermia
01/2000
1Lung Neoplasms (Lung Cancer)
01/2000

Drug/Important Bio-Agent (IBA)

4MicroRNAs (MicroRNA)IBA
12/2016 - 06/2010
4Proteins (Proteins, Gene)FDA Link
02/2006 - 03/2000
4NeurotoxinsIBA
05/2002 - 01/2000
3EnzymesIBA
11/2006 - 01/2000
3salsolineIBA
05/2002 - 01/2000
2Selegiline (E250)FDA LinkGeneric
01/2007 - 01/2000
2propargylamineIBA
01/2007 - 01/2006
2IronIBA
05/2006 - 01/2006
2neuromelaninIBA
05/2006 - 01/2006
2Proteasome Endopeptidase Complex (Proteasome)IBA
05/2006 - 10/2004
2Messenger RNA (mRNA)IBA
07/2003 - 12/2001
2Dopamine (Intropin)FDA LinkGeneric
05/2002 - 01/2000
2Arsenic Trioxide (Trisenox)FDA Link
10/2000 - 03/2000
1Carrier Proteins (Binding Protein)IBA
12/2016
1Microphthalmia-Associated Transcription FactorIBA
12/2016
1Biological ProductsIBA
12/2016
1Adenosine Monophosphate (AMP)IBA
12/2016
1CytokinesIBA
02/2013
1InterferonsIBA
02/2013
1RNA (Ribonucleic Acid)IBA
06/2010
1Biomarkers (Surrogate Marker)IBA
01/2007
1rasagiline (Azilect)FDA Link
01/2007
1SphingolipidsIBA
11/2006
1Amyloid (Amyloid Fibrils)IBA
02/2006
1Amyloid beta-PeptidesIBA
02/2006
1Monoamine Oxidase (MAO)IBA
01/2006
1UbiquitinIBA
10/2004
1DEAD-box RNA HelicasesIBA
07/2003
1Interleukin-3 (Interleukin 3)IBA
01/2003
1phosphoinositide-3,4,5-triphosphateIBA
01/2003
1RNA Helicases (RNA Helicase)IBA
12/2001
1fragile histidine triad proteinIBA
11/2000
11-dodecylpyridoxal (PLD)IBA
11/2000
1phospholipase D2IBA
11/2000
1Histidine (L-Histidine)FDA Link
11/2000
1Indicators and Reagents (Reagents)IBA
03/2000
1Acetylcysteine (Siran)FDA LinkGeneric
03/2000
1ArsenicIBA
03/2000
1Caspase 3 (Caspase-3)IBA
03/2000
1Glutathione (Reduced Glutathione)IBA
03/2000
1DNA (Deoxyribonucleic Acid)IBA
01/2000
1salsolinol N-methyltransferaseIBA
01/2000
1isoquinolineIBA
01/2000
1Pharmaceutical PreparationsIBA
01/2000

Therapy/Procedure

3Therapeutics
12/2012 - 03/2000
2Drug Therapy (Chemotherapy)
01/2003 - 01/2000